The regulation of NADL-glutamate dehydrogenase inAspergillus nidulans
نویسندگان
چکیده
منابع مشابه
The Regulation of Nicotinamide-Adenine Dinucleotide-Linked Glutamate Dehydrogenase in Aspergillus nidulans
When wild-type cells of Aspergilbrs nidulans were grown on -N medium (minimal medium minus a N source) with ammonia, glutamate, aspartate or alanine as sole N sources there was low L-glutamate-NAD oxidoreductase (EC 1.4.1.2) activity. A similar result was obtained when cells were grown as before and then deprived of N for periods of up to 6h. However, it was found that when cells were transferr...
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The activity of bovine liver glutamate dehydrogenase is affected in several ways depending on substrate concentrations and pH. At pH 6.5 and below, both oxidative deamination and reductive amination reactions are inhibited by ADP. At pH 7.0 and above both activatory and inhibitory effects can be observed depending on substrate concentrations. The effects are explicable in terms of a model with ...
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The activity of the nicotinamide adenine dinucleotide-dependent glutamate dehydrogenase in Bacillus subtilis was influenced by the carbon source, but not the nitrogen source, in the growth medium. The highest specific activity for this enzyme was found when B. subtilis was grown in a minimal or rich medium that contained glutamate as the carbon source. It is proposed that glutamate dehydrogenas...
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The NADP-specific glutamate dehydrogenase (NADP-GDH) activity of Aspergillus nidulans was rapidly lost from cultures starved for a carbon source. This loss of NADP-GDH was blocked by protein synthesis inhibitors. Glutamate repressed NADP-GDH but did not cause rapid loss of activity. Since NADP-GDH is involved in the participation of ammonium in the regulation of nitrogen metabolism, the loss of...
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1. The effect of NADH and the non-competitive inhibitor GTP on the optical-rotatory-dispersion properties of glutamate dehydrogenase has been studied. 2. Analysis of the data in terms of the a(0) and b(0) parameters of the Moffitt-Yang equation indicates that a conformational change is induced either by NADH or by GTP in the presence of small amounts of NADH. 3. Sedimentation measurements under...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1974
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300014713